Product Information

[Neuromics] GFAP, HOT & NEW Cells Products

 

HOT  GFAP

 

 

: Human GFAP는 astrocytes에서 발현된 49,749 달톤 단백질 (432 아미노산)입니다. GFAP는 중간 필라멘트 단백질이며 세포 골격의 세포 내 구조 성분으로서 작용합니다. 배아 및 태아 생활 동안, GFAP는 또한 CNS의 방사상 아교 세포에 의해 발현되며, GFAP 유전자의 다양한 돌연변이는 백혈병 중 하나 인 알렉산더 병을 생성합니다.

따라서, GFAP에 대한 항체는 astrocytic cells 및 신경 줄기 세포의 마커로서 매우 유용합니다. 또한, astrocytic cells로부터 유래 된 많은 유형의 뇌종양은 GFAP를 많이 발현합니다.

 

Product Details

 

CATALOG NUMBER: RA22101

APPLICATIONS: ICC, WB, IHC

TYPE: Rabbit IgG

IMMUNOGEN: Recombinant GFAP and purified bovine GFAP

STORAGE: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

FORMAT A: Whole serum

FORMAT B: liquid

SPECIES REACTIVITY: Human, Mouse, Rat, Cat

ENTREZ: 2670

UNIPROT: P14136

SIZE: 100 ul

DOWNLOADS: Datasheet (pdf)

 


 

* Mixed neuron-glial cultures stained with rabbit GFAP (red channel) and chicken vimentin (green channel). The fibroblastic cells contain only vimentin and so are green, while astrocytes contain either vimentin and GFAP, so appearing golden, or predominantly GFAP, in which case they appear red. Blue is nuclear DNA stain. Protocol on data-sheet

 

 

* Injection of rhHsp70 did not result in overt changes in glial cell activation. Lumbar spinal cord tissue was collected from treated and untreated G93A SOD1 or WT mice on P90. Twenty-five micrograms of protein per lane was loaded into each lane and Western blotting was performed to assess relative levels of GFAP and Iba1. When normalized to actin, quantification of the bands confirmed no change in expression (data not shown). doi:10.1523/JNEUROSCI.4057-07.2007

 

 

New Released Cells

 

Name Catalog # Type Species Applications Size
Cerebellum PC35139 Primary Cells Mouse Cell Assays Cerebellum
Eyeballs PC35140 Primary Cells Mouse Cell Assays Eyeballs
Glioblastoma CAFs CAF03 Cell Growth Media Human Cell Assays 1,000,000 Cells
Hypothalamus PC35141 Primary Cells Mouse Cell Assays Hypothalamus >400,000 Cells
Midbrain PC35142 Primary Cells Mouse Cell Assays Midbrain, >300,000 Cells
Pineal Gland PC35143 Primary Cells Mouse Cell Assays Pineal Gland
Retinal Pigment Epithelial Cells RPE001 Primary Cells Human Cell Assays 500,000 Cells
Sciatic Nerve PC35144 Primary Cells Mouse Cell Assays Sciatic Nerve
Septum PC35145 Primary Cells Mouse Cell Assays Septum
Spinal Cord PC35146 Primary Cells Mouse Cell Assays Spinal Cord, >200,000 Cells
Striatum PC35147 Primary Cells Mouse Cell Assays Striatum, >3.9 Million Cells

 

 

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(주)모아바이오 주소/연락처/팩스