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제품 설명 

Bamlanivimab Biosimilar – Anti-Covid Spike RBD mAb – Research Grade

제품 번호

PX-TA1031

제품 특징

Description of Bamlanivimab Biosimilar - Anti-Covid Spike RBD mAb - Research Grade

General information on Anti-SARS-CoV2 Spike RBD (Bamlanivimab) Monoclonal Antibody

Bamlanivimab is a synthetic monoclonal antibody (mAb) that was developped from the first blood samples from COVID-19 recovered patients in the United States. Bamlanivimab is a neutralizing IgG1 mAb targetting the SARS-CoV-2 spike, which prevents the virus from entering human cells. It has been found to recognize first type and variants referenced as PX-COV-P046 and PX-COV-P052.

QC & Validation Data

SDS-PAGE for Bamlanivimab Biosimilar - Anti-Covid Spike RBD mAb

Bamlanivimab Biosimilar - Anti-Covid Spike RBD mAb, on SDS-PAGE under reducing and non-reducing conditions. The gel was stained overnight with Coomassie Blue. The purity of the antibody is greater than 95%.

Publications

• - Efficient Neutralization of SARS-CoV-2 Omicron and Other VOCs by a Broad Spectrum Antibody 8G3,Hang Ma, Chien-Te K. Tseng, Huifang Zong, Yunji Liao, et al., bioRxiv 2022.02.25.482049; doi: https://doi.org/10.1101/2022.02.25.482049
• - Evelien Vanderlinden, Arnaud Boonen, Sam Noppen, Geert Schoofs, Maya Imbrechts, Nick Geukens, Robert Snoeck, Annelies Stevaert, Lieve Naesens, Graciela Andrei, Dominique Schols, PRO-2000 exhibits SARS-CoV-2 antiviral activity by interfering with spike-heparin binding, Antiviral Research, Volume 217, 2023, 105700, ISSN 0166-3542, https://doi.org/10.1016/j.antiviral.2023.105700.

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