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Neuromics

[Neuromics] Human Lung Adenocarcinoma CAFs

Cat-No. CAF117



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Human Lung Adenocarcinoma CAFs




제품 번호


CAF117




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Product Details
Catalog Number: CAF117
Applications: Cell Assays
Type: Human Primary CAFs
Storage: Keep frozen in liquid nitrogen until plating
Shipping: Frozen (Dry Ice/Liquid Nitrogen)
Format A: Frozen
Species Reactivity: Human
Downloads: Datasheet (pdf)
Downloads: COA-CAF117 (pdf)


Product Sizes
Size
1,000,000 cells


Carcinoma associated fibroblasts (CAFs) have recently been implicated in important aspects of epithelial solid tumor biology such as neoplastic progression, tumor growth, angiogenesis, and metastasis. Human Lung Adenocarcinoma CAFs are isolated from human lung tumor tissue. Cells are grown in T75 tissue culture flasks. Prior to shipping, cells at passage 1 are detached from flasks and immediately cryo-preserved in vials. Each vial contains at least 1,000,000 cells.

 

Human Lung Adenocarcinoma CAFs can be used for the assay of cell-cell interaction, adhesion, PCR, Western blot, immunoprecipitation, immunofluorescent flow cytometry, or generating cell derivatives for desired research applications. Cells can be expanded for 3-5 passages.

 

Cells are prepared and manufactured in an ISO 9001:2015 certified environment and ISO 5 cleanroom.


Product Highlights:


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Product Publications
  1. Yi Yuan. (2024). Modulating Tumor Immunity to Suppress Tumor Progression in Non-Small Cell Lung Cancer.  Georgia State University, Doctoral Dissertation.
  2. Namrata Bora-Singhal, Durairaj Mohankumar, Biswarup Saha, Christelle M. Colin, Jennifer Y. Lee, Matthew W. Martin, Xiaozhang Zheng, Domenico Coppola, and Srikumar Chellappan. (2020). Novel HDAC11 Inhibitors Suppress Lung Adenocarcinoma Stem Cell Self-Renewal and Overcome Drug Resistance by Suppressing Sox2.  Scientific Reports, 10:4722. doi: 10.1038/s41598-020-61295-6


Lung CAFs in culture. Grown using CAF Growth Media (cat. CAFM03)


Lung CAFs in culture. Grown using CAF Growth Media (cat. CAFM03)


Expression of integrin β3 and α-SMA in lung adenocarcinoma CAFs compared to normal lung fibroblasts. Data courtesy of Yi Yuan, Georgia State University.




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