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제품 설명

Human iPSC - Motor Neurons (ALS Patient, Sporadic)

제품 번호

IPS014

제품 특징

Product Details

These human spinal motor neurons (MNs) are derived from induced Pluripotent Stem Cells (iPSCs) reprogrammed from a donor with a confirmed diagnosis of sporadic Amyotrophic Lateral Sclerosis (sALS). The differentiation process utilizes a directed, floor-plate based protocol to generate a highly pure population of cells expressing key motor neuron markers.

This product provides a physiologically relevant in vitro model of sALS, which accounts for ~90% of all ALS cases. These neurons recapitulate key disease phenotypes, including increased susceptibility to cellular stress, altered mitochondrial function, and potential TDP-43 proteinopathy. They are an essential tool for investigating the mechanisms of motor neuron degeneration, screening neuroprotective compounds, and developing personalized medicine approaches for ALS.

Cells are prepared and manufactured in an ISO 9001:2015 certified environment and ISO 5 cleanroom.

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