MD Bioproducts는 생명공학 전문 회사로, 면역학 및 염증 연구를 위한 제품과 서비스를 제공합니다.

제품 설명

Collagen Type I Antibody, anti-Rat, 100 uL

제품 번호

203004-1

제품 특징

Description

Collagen type I polyclonal antibody (rabbit anti-rat) purified from rabbits injected with type I collagen that was extracted/purified from rat skin. IgG fraction, freeze-dried (0.5 ml). Reconstitute with 0.5 ml di H2O and store aliquots at -20°C.

Type I collagen is the most abundant form of collagen in the human body and is synthesized mainly by fibroblasts, osteoblasts, odontoblasts and chondroblasts. It is located in the extracellular matrix of many tissues of the body including cartilage, bone, tendon, skin and the sclera of the eye. Type I collagen is composed of two pro-_1(I) chains, produced from the COL1A1 gene, and one pro-_2(I) chain, produced from the COL1A2 gene. Mutations in the genes that produce collagen type I are responsible for causing various health conditions including Ehlers-Danlos syndrome, osteogenesis imperfecta, osteoporosis and Caffey disease.

Data/Specifications: 

• Format: IgG fraction, freeze-dried (0.5 ml). Reconstitute with 0.5 ml di H2O and store aliquots at -20°C.
• Specificity (% at 1:200 RIA dilution):
• Rat Collagen, Type I : 100%
• Rat Collagen, Types II, III, V : < 0.1%
• Human, mouse, chicken Collagen Type I: < 0.1%
• Rat elastin: <0.1%