(주)모아바이오

YEASEN

[YEASEN] GTP Solution GMP-grade (100 mM)

Cat-No. 10132ES

YEASEN은 생명과학 연구 및 진단을 위한 고품질의 연구용 시약과 기기를 제공하는 글로벌 바이오 기업입니다.

제품 설명

GTP Solution GMP-grade (100 mM)

제품 번호

10132ES

제품 설명

Description

GTP, Guanosine-5'-triphosphate, can be used in various of molecular biology applications, such as in vitro transcription, RNA amplification, siRNA synthesis, etc. In addition, GTP plays an important role in signal transduction as a phosphate or pyrophosphate messenger: GTP can activate G proteins, which can induce multiple protein kinase mediated cascade reations, causing a variety of cytological behaviors, such as cell proliferation, differentiation, etc. GTP can also be used as a high-energy precursor of single nucleotides to participate in the synthesis of DNase and RNase.

This product is a transparent colorless aqueous solution prepared with GTP tris solution, and free of DNase and RNase contamination.

This product is produced in accordance with GMP process requirements and provided in liquid form.

Feature

Validated, product-specific process and analytical methods
Product-specific stability
Documentation follows applicable GMP guidelines
AOF production process and raw materials (TSE & BSE)
Nitrosamine statement
Regulatory support documents available
Large-scale production
Nucleotide in the multiple salt form（Na⁺, Tris etc) always available to meet different downstream application needs

Application

RNA synthesis and amplification
Building block for in vitro transcription

Specification

CAS No	86-01-1 (free acid); 36051-31-7 (3Na salt)
Formula	C₁₀H₁₃N₅Na₃O₁₄P₃ (free acid)
Molecular Weight	589.13 g/moL (free acid)
Purity (HPLC)	≥ 99%
Content	100 mM ± 3 mM
Structure

Component

Components No.	Name	10132ES03	10132ES10	10132ES60
10132	CTP Solution GMP-grade (100 mM)	1 mL	10 mL	100 mL

Shipping and Storage

The product is shipped with dry ice and can be stored at -15℃ ~ -25℃ for two years.

Figures

Standard RNA Synthesis

Figure 1. Standard RNA was synthesized in vitro using T7 RNA synthesis kit.

The reaction was incubated in PCR instrument at 37℃ for 2h, and then purified by magnetic beads (Cat#12602). The yield result was analyzed by NanoDrop spectrophotometer as shown in Figure 1.

Capped RNA Synthesis

Figure 2. Synthesis of capped RNA in vitro.

The reaction was incubated in PCR instrument at 37℃ for 2h, and then purified by magnetic beads (Cat#12602). The yield result was assayed by NanoDrop spectrophotometer as shown in Figure 2A. The integrity result was analyzed by capillary electrophoresis as shown in Figure 2B.

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