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제품 설명
Anti-DXD Mouse mAb
제품 번호
31902ES60 - 100 μg
31902ES80 - 1mg
제품 설명
Exatecan（DXD）is a synthetic derivative of the naturally occurring compound camptothecin. it binds to the topoisomerase 1-DNA complex, preventing DNA re-ligation which results in the accumulation of DNA strand breaks and ultimately leads to cell death.
Cat.No. | 31902ES60/31902ES80 |
Size | 100 μg/1 mg |
Source | Monoclonal anti-DXD antibody, is produced from a hybridoma which was obtained from a mouse immunized with DXD. |
Buffer | 1×PBS, pH7.4. |
Type | Monoclonal Antibody |
Isotype | IgG1 |
Host | Mouse |
Concentration | 1 mg/mL |
Purity | ＞98% as determined by reduced SDS-PAGE ＞98% as determined by non-reduced SDS-PAGE > 98% as determined by SEC-HPLC |
Activity | EC50=41.4 ng/mL by ELISA |
Application | ELISA |
This product should be stored at -25~-15℃ for one year, do not freeze.
SDS-PAGE
Anti-DXD mouse mAb on SDS-PAGE under reduced condition. The purity is 98.2%；
Anti-DXD mouse mAb on SDS-PAGE under non-reduced condition. The purity is 98.4%.
SEC-HPLC
The purity of Anti-DXD mouse mAb is 99% as determined by SEC-HPLC.
ELISA Data
Dose response curve shows that the EC50 of Anti-DXD mouse mAb is 41.4 ng/mL.
Ver.EN20240725
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