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제품 설명
Anti-MMAE Mouse mAb
제품 번호
31903ES60 - 100 μg
31903ES80 - 1mg
제품 설명
MMAE, or monomethyl auristatin E, is a potent cytotoxic agent commonly used in the development of antibody-drug conjugates (ADCs) for targeted cancer therapy. It is an antimitotic agent which inhibits cell division by blocking the polymerization of tubulin.
Cat.No. | 31903ES60/31903ES80 |
Size | 100 μg/1 mg |
Source | Monoclonal anti-MMAE antibody, is produced from a hybridoma which was obtained from a mouse immunized with MMAE. |
Buffer | 1×PBS, pH7.4. |
Type | Monoclonal Antibody |
Isotype | IgG1 |
Host | Mouse |
Concentration | 1 mg/mL |
Purity | ＞94% as determined by reduced SDS-PAGE ＞97% as determined by non-reduced SDS-PAGE > 98% as determined by SEC-HPLC |
Activity | EC50=6.3 ng/mL by ELISA |
Application | ELISA |
This product should be stored at -25~-15℃ for one year, do not freeze.
SDS-PAGE
Anti-MMAE mouse mAb on SDS-PAGE under reduced condition. The purity is 94.7%；
Anti-MMAE mouse mAb on SDS-PAGE under non-reduced condition. The purity is 97.6%.
SEC-HPLC
The purity of Anti-MMAE mouse mAb is 98% as determined by SEC-HPLC.
ELISA Data
Dose response curve shows that the EC50 of Anti-MMAE mouse mAb is 6.3 ng/mL.
Ver.EN20240725
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