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제품 설명
Anti-DM1 Mouse mAb
제품 번호
31901ES60 - 100 μg
31901ES80 - 1mg
제품 설명
DM1, also known as maytansine, is a microtubulin inhibitor, potentially conjugated with monoclonal antibodies to form antibody-drug conjugates(ADCs). DM1 as the toxin component of ADCs, exhibits strong anti-tumor activity by inhibiting cell division and inducing apoptosis.
Cat.No. | 31901ES60/31901ES80 |
Size | 100 μg/1 mg |
Source | Monoclonal anti-DM1 antibody, is produced from a hybridoma which was obtained from a mouse immunized with DM-1. |
Buffer | 1×PBS, pH7.4. |
Type | Monoclonal Antibody |
Isotype | IgG1 |
Host | Mouse |
Concentration | 1 mg/mL |
Purity | ＞94% as determined by reduced SDS-PAGE ＞97% as determined by non-reduced SDS-PAGE > 98% as determined by SEC-HPLC |
Activity | EC50=8.6 ng/mL by ELISA |
Application | ELISA |
This product should be stored at -25~-15℃ for one year, do not freeze.
SDS-PAGE
Anti-DM1 mouse mAb on SDS-PAGE under reduced condition. The purity is 93.4%；
Anti-DM1 mouse mAb on SDS-PAGE under non-reduced condition. The purity is 98.0%.
SEC-HPLC
The purity of Anti-DM1 mouse mAb is 96.8% as determined by SEC-HPLC.
ELISA Data
Dose response curve shows that the EC50 of Anti-DM1 mouse mAb is 8.6 ng/mL.
Ver.EN20240725
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