Myosin heavy chain 11 Antibody, mAb, Rabbit

제품 번호

A04707-50

제품 특징

Overview

Specificity	This product is specific to Myosin heavy chain 11
Host Species	Rabbit
Immunogen	A synthesized peptide derived from human Myosin heavy chain 11
Species Reactivity	Human; Mouse
Conjugate	Unconjugated

Applications

Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

Application	Recommended Usage
Western Blot	1:1000-1:2000
Immunohistochemistry (IHC)	1:100-1:200

Properties

Form	Liquid
Storage Buffer	Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage Instructions	Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification	Affinity-chromatography
Isotype	Rabbit IgG
Clonality	Monoclonal

Background

Target Background

The protein encoded by this gene is a smooth muscle myosin belonging to the myosin heavy chain family. The gene product is a subunit of a hexameric protein that consists of two heavy chain subunits and two pairs of non-identical light chain subunits. It functions as a major contractile protein, converting chemical energy into mechanical energy through the hydrolysis of ATP. A chromosomal rearrangement involving this gene is associated with acute myeloid leukemia of the M4Eo subtype. Mutations in this gene are associated with visceral myopathy, megacystis-microcolon-intestinal hypoperistalsis syndrome 2, and familial thoracic aortic aneurysm 4.

Synonyms

AAT4; FAA4; MYH11; SM1; SM2; SMHC; SMMHC;

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.

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Genscript

[Genscript] Myosin heavy chain 11 Antibody, mAb, Rabbit

Cat-No. A04707-50

Myosin heavy chain 11 Antibody, mAb, Rabbit