MonoFab Anti-VHH Cocktail [Biotin], Fab

제품 번호

A01854-200

제품 특징

Overview

Specificity	The product is specific for VHH antibodies derived from camelids (including llama, alpaca, and camel) as well as humanized VHH antibodies. It has no significant cross-reactivity with mouse, rat, rabbit, goat or human immunoglobulins.
Host Species	Rabbit
Immunogen	VHH antibody
Conjugate	Biotin

Applications

Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

Application	Recommended Usage
ELISA	1:10-1:100
Sandwich ELISA	A02298 (C)-A02348 (D)
Western Blot	User-optimized
Immunohistochemistry (IHC)	User-optimized
Immunocytochemistry/Immunofluorescence (ICC/IF)	User-optimized

Properties

Form	Liquid
Storage Buffer	Supplied in PBS (pH 7.2), containing 10 mg/ml BSA, 0.03% ProClin300 and 50% glycerol.
Concentration	0.5 mg/ml
Storage Instructions	Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed.
Purification	His-tag affinity purification. Note: The product contains a His tag for purification purposes.
Isotype	Rabbit Fab
Clonality	Monoclonal antibody cocktail
Note	GenScript can customize this product per customer's request including product size, buffer components, etc.

Background

Target Background

A camelid single-domain antibody (sdAb, called Nanobody by Ablynx) is a peptide chain about 110 amino acids long comprising one variable domain of a heavy-chain antibody (VHH fragment). Like a whole antibody, a single-domain antibody is able to bind selectively to a specific antigen. Such antibodies allow a broad range of applications in biotechnical as well as therapeutic fields due to their small size, simple production, and high affinity. However, their sequences may increase the risk of immunogenicity and cause anti-drug antibody (ADA) development in humans, and thus, sdAbs are routinely humanized during development.

Synonyms

VHH, Nanobody, Single-Domain Antibody, sdAb, HCAb-Derived Variable Domain, Heavy chain antibody, HcAb, Heavy Chain-Only Antibody Fragment, Camelid Single-Domain Antibody, Variable Domain of Heavy Chain Antibody, Camelid antibody, Humanized sdAb, Humanized VHH

For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.

Genscript의 모든 제품을 만나 보세요!

Reagent Services

Products

Genscript - Official Distributor in South Korea "Morebio" 한국 공식 대리점 "모아바이오"

제품소개

제품상세페이지

Genscript

[Genscript] MonoFab Anti-VHH Cocktail [Biotin], Fab

Cat-No. A02348-200

MonoFab Anti-VHH Cocktail [Biotin], Fab