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YEASEN

[YEASEN] N1-Me-Pseudo UTP Tris Solution GMP-grade (100 mM)

Cat-No. 10657ES

YEASEN은 생명과학 연구 및 진단을 위한 고품질의 연구용 시약과 기기를 제공하는 글로벌 바이오 기업입니다.

제품 설명

N1-Me-Pseudo UTP Tris Solution GMP-grade (100 mM)

제품 번호

10657ES

제품 설명

Description

N1-Me-Pseudo UTP solution is one of the most commonly used modified nucleoside triphosphates. It is mostly used as the reaction substrate or coenzyme of enzymes, such as in vitro transcription, RNA amplification, siRNA synthesis, etc. The modified mRNA containing pseudouridine has better nuclease stability and translation characteristics and changes the innate immune receptor and in vitro transcription. The interaction of RNA has a wide range of applications in the field of therapy and diagnosis.
This product is produced in accordance with GMP process requirements and provided in liquid form.

Feature

Validated, product-specific processes and analytical methods
Product-specific stability
Documentation follows applicable GMP guidelines
AOF production process and raw materials (TSE & BSE)
Nitrosamine statement
Regulatory support documents available
Large-scale production
The increased IVT yield and the decreased dsRNA content under the optimized Tris NTP reaction system

Application

RNA synthesis and amplification
Building block for in vitro transcription

Components

Components No.	Name	10657ES20	10657ES70	10657ES80	10657ES10	10657ES60
10657	N1-Me-Pseudo UTP Tris Solution GMP-grade (100 mM)	20 μL	100 μL	1 mL	10 mL	100 mL

Specification

CAS No.	1428903-59-6 (free acid)
Molecular formula	C₁₀H₁₇N₂O₁₅P₃ (free acid)
Molecular weight	498.17 g/moL (free acid)
Purity	≥ 99%
Content	100mM ± 3mM
Structure

Shipping and Storage

The product should be stored at -25℃ ~ -15℃ for two years.

Figures

Increased the IVT yield

Figure 1. The IVT yield was significantly increased under the optimized Tris NTP reaction system, compared with the sodium NTP reaction system.
- Decreased the dsRNA content
Figure 2. The content of dsRNA was significantly decreased under the optimized Tris NTP reaction system, compared with the sodium NTP reaction system. The content of dsRNA was detected by the Dot Blot method.