GenScript는 2002년에 설립된 미국 뉴저지주 기반의 생명과학 기업으로,
유전자 합성, 단백질 공학, 항체 개발 등 다양한 생명과학 연구 서비스를 제공합니다.
모아바이오는 Genscript의 한국 공식 대리점 입니다.
제품 설명
MonoMethyl-Histone H3 (K14) Antibody, mAb, Rabbit
제품 번호
A05037-50
제품 특징
| Specificity | This product is specific to MonoMethyl-Histone H3 (K14) |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human Histone H3.1 around the methylation site of K15 |
| Species Reactivity | Human; Mouse |
| Conjugate | Unconjugated |
| Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product. |
| Application | Recommended Usage |
|---|
| Western Blot | 1:1000-1:2000 | | Immunocytochemistry/Immunofluorescence (ICC/IF) | 1:50-1:200 | | Flow Cytometry | 1:20-1:100 |
|
| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
| Target Background | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Synonyms | Histone H3.1, Histone H3, HIST1H3A; |
For research use only. Not intended for human or animal clinical trials, therapeutic or diagnostic use.
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