ichorbio는 차세대 oncology 혁신을 위해 연구를 지속적으로 발전시키며, 합리적인 가격으로
고품질의 Research Grade Biosimilars 와 In vivo Antibodies 제품들을 전문적으로 생산하는 영국 제조사입니다.
제품 설명
Bulk Anti-Human CD2 (G11) Antibody
제품 번호
SKU: ICH1001
제품 특징
Product Benefits:
ichorbio's anti-Human CD2 antibody (G11) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from Bio X Cell at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.5EU/mg) at an even higher purity (98% versus 95%). ichorbio: the best antibodies for in vivo research.
Target:
CD2
Clone:
G11
Isotype:
Mouse IgG2a
Other Names:
Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5
Uniprot:
Host:
Mouse
Species Reactivity:
Human
Specificity:
Anti-Human CD2 antibody (G11) recognizes Human CD2. Anti-Human CD2 recognizes a cell surface glycoprotein (Mr 45-59 kDa) on human lymphocytes
Purification Method:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution:
The CD2 antigen is present on approximately 80% of normal peripheral blood lymphocytes, >95% of thymocytes, 100% of mature circulating T-cells and a subset of NK cells.
Background:
Appropriate pairs of anti-CD2 antibodies will stimulate peripheral T-cell proliferation and effector function. The CD2 molecule has been shown to be the receptor for leukocyte function antigen (LFA-3/CD58), the binding of which augments T-cell activation mediated by the T-cell antigen receptor (TCR). Anti-Human CD2 can be used to deplete CD2 positive cells by complement-mediated cytotoxicity. Analyses of NK lymphocyte subsets and identification of lymphomas and leukemias of T-cell origin have been done using Anti-CD2 antibodies.
Concentration:
1.0 - 5.0 mg/ml
Formulation:
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity:
>95% by SDS-PAGE and HPLC
>98% by SDS-PAGE and HPLC
Endotoxin:
≤ 1.0 EU/mg as determined by the LAL method
≤ 0.75 EU/mg as determined by the LAL method
Aggregation:
Aggregation level ≤ 5%
Aggregation level ≤ 1%
Storage:
This antibody is stable for at least 4 weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C or -80°C. Avoid repeated freeze thaw cycles.
Applications:
Western Blot, Functional Assays
Application Notes:
Each investigator should determine their own optimal working dilution for specific applications.
Use:
Products are for research use only.
Isotype Control:
Mouse IgG2a In Vivo Isotype Control - Low Endotoxin [C1.18.4] (ICH2245)
Alternative Names:
ichorbio의 모든 제품들을 만나보세요!
ichorbio - Official Distributor in South Korea "Morebio" ichorbio의 한국 공식 대리점 "모아바이오"
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