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제품 설명
PE/Cyanine7 Anti-Human CD274/PD-L1 Antibody[29E.2A3]
제품 번호
E-AB-F1133H
제품 특징
Product Details
| Background | CD274, also known as PD-L1 and B7-H1, is type I transmembrane glycoprotein that serves as a ligand for CD279 (PD-1). This interaction is believed to regulate the balance between the stimulatory and inhibitory signals needed for responses to microbes and maintenance of self-tolerance. CD274 is involved in the costimulation of T cell proliferation and IL-10 and IFN-γ production in an IL-2-dependent and CD279-independent manner. Conflicting data has shown that CD274 can inhibit T cell proliferation and cytokine production, and alternatively, enhance T cell activation. Other studies suggest that CD274 may signal bidirectionally, raising interesting implications for its expression in a wide variety of cell types, including T and B cells, antigen-presenting cells, and nonhematopoietic cells. |
| Alternate Names | B7H1PD-L1PDCD1L1PDCD1LG1PDL1, B7 homolog 1, B7-H, B7-H1, Programmed cell death ligand 1 |
| Swissprot | |
| Clone No | |
| Host | Mouse |
| Reactivity | Human |
| Isotype | Mouse IgG2b, κ |
| Isotype Control | |
| Application | FCM |
| Form | Liquid |
| Conjugation | PE/Cyanine 7 |
| Conjugation information | PE/Cyanine7 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 775 nm (e.g., a 780/60 nm bandpass filter). |
| Spectrum |  |
| Storage Buffer | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Storage | This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze. |
| Expiration date | 12 months |
| Shipping | Ice bag |
Related Products
| Cat.No. | Product Name | Sizes |
|---|---|---|
| E-AB-F11330 | AF/LE Purified Anti-Human CD274/PD-L1 Antibody[29E.2A3] | 500μg , 50μg , 1mg |
| E-AB-F1133A | Purified Anti-Human CD274/PD-L1 Antibody[29E.2A3] | 100μg , 25μg |
| E-AB-F1133B | Biotin Anti-Human CD274/PD-L1 Antibody[29E.2A3] | 100μg , 25μg |
| E-AB-F1133C | FITC Anti-Human CD274/PD-L1 Antibody[29E.2A3] | 100Tests , 20Tests , 100Tests×2 |
| E-AB-F1133D | PE Anti-Human CD274/PD-L1 Antibody[29E.2A3] | 100Tests , 20Tests , 100Tests×2 |
| E-AB-F1133E | APC Anti-Human CD274/PD-L1 Antibody[29E.2A3] | 100Tests , 20Tests , 100Tests×2 |
| E-AB-F1133G | PE/Cyanine5 Anti-Human CD274/PD-L1 Antibody[29E.2A3] | 100Tests , 20Tests , 100Tests×2 |
| E-AB-F1133J | PerCP/Cyanine5.5 Anti-Human CD274/PD-L1 Antibody[29E.2A3] | 100Tests , 20Tests , 100Tests×2 |
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