Synbio Technologies는 혁신적인 합성 생물학 솔루션을 제공하여 생명과학 연구 및 개발을 지원하는 기업입니다.

The General Introduction of siRNA/miRNA Synthesis

RNA interference (RNAi) is a powerful gene silencing tool, crucial for biological and therapeutic research, especially in targeting undruggable diseases like cancer. siRNA binds to target mRNA in the RISC complex to inhibit its function, while miRNAs regulate mRNA degradation or translation, with dysregulation linked to cancer.

Synbio Technologies offers highly customized siRNA and miRNA synthesis services, ensuring high-quality products through expert synthesis techniques and rigorous quality controls. In addition, Synbio Technologies provides various chemically modified siRNAs for enhanced stability and efficacy, as well as various miRNA products, including mimics, inhibitors, and controls, to support diverse research needs.

Highlights

Provide Diversified siRNA & miRNA Products

Expert Technical Team to Provide Support

Strictly Confidential Project Details

Strict Quality Control to Avoid Contamination

Service Details

 siRNA synthesis

* For more information please contact us at quote@synbio-tech.com.

Synbio Technologies also provides a guaranteed siRNA service. The three/four designed and delivered siRNA ensure at least one siRNA can effectively inhibit the expression of the target gene. The resulting inhibition efficiency will be at least 70% (The transfection efficiency will be at least 90%).

miRNA synthesis

Deliverables

Lyophilized RNA

 Certificate of Analysis (COA)

 QC Report (MS/HPLC)

FAQs

How to choose a suitable siRNA sequence?

Specificity: Ensure that the siRNA sequence specifically targets the target gene to avoid off-target effects.

Effectiveness: Screen siRNA sequences with high silencing efficiency.

Stability: Optimize the siRNA sequence to improve its stability and effectiveness in the cell.

How to detect the effect of RNAi?

qPCR: Quantitatively detect changes in mRNA levels of target genes.

Western Blot: Detect the expression level of the protein encoded by the target gene.

Fluorescence Microscopy: Observe the distribution and expression of siRNA or shRNA in cells by fluorescent labeling.

How do I store RNA oligos?

RNA oligos should be stored at -20°C or lower in RNase-free water or specialized RNA storage solutions to prevent degradation. Avoid repeated freeze-thaw cycles during storage to maintain their integrity.

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SERVICES

DNA Synthesis

Vector Selection

Molecular Biology

Oligo Synthesis

RNA Synthesis

Variant Libraries

CRISPR Libraries

Oligo Pools

Virus Packaging

Gene Editing

Protein Expression

Antibody Services

Peptide Services

DNA Data Storage

PRODUCTS

Standard Oligo

Standard CRISPR Libraries

Standard CRISPR Plasmid

ProXpress

Protein Products

ONE STOP SOLUTION

High Performing DNA-RNA-Protein Molecules

Oligonucleotide Diagnostics & Therapeutics

Precision Gene Editing

Value Chain

SYNBIO Technologies - Exclusive Distributor in South Korea "Morebio" 한국 독점 대리점 "모아바이오"