미국 Accegen은 생명과학 연구와 의약품 개발을 지원하기 위해 다양한 세포주와 생물학적 제품을 제공하는 바이오 제품 제조 기업입니다.
제품 설명
TT
제품 번호
ABC-TC484S
제품 특징
The TT cell line, originating from a thyroid medullary carcinoma specimen obtained through needle biopsy from a 77-year-old female, exhibits an epithelial-like morphology and is renowned for its sustained high-level production of calcitonin and CEA. Chromosomal analysis of the cell line and tumors induced in nude mice unveils an aneuploid human karyotype marked by several aberrant chromosomes. TT cells demonstrate slow growth kinetics, forming cell clusters that achieve only 10-20% confluence by day 1 of incubation and gradually reach 80-90% confluence by day 18. Notably, sporadic floating cells are discernible during cultivation and can be resuspended into the culture medium.
Why choose TT from AcceGen?
The TT cell line is characterized by its exceptional quality and high viability, meticulously maintained under optimal incubation conditions. Daily scrutiny for bacterial and fungal contamination is conducted, and it consistently tests negative for mycoplasma. The cell line’s identity is verified using STR analysis, ensuring rigorous quality control throughout its use in research and experimentation.
The TT cell line serves as a valuable tool in cancer research, particularly in the context of thyroid medullary carcinoma. It plays a crucial role in conducting 3D cell culture experiments to simulate the tumor microenvironment. Researchers utilize TT cells to evaluate the impact of potential drugs or therapeutic strategies on crucial aspects of medullary thyroid cancer, including invasion, migration, proliferation, apoptosis, cell cycle regulation, and the modulation of miRNAs. This cell line aids in uncovering mechanisms with potential anti-tumor activity against medullary thyroid carcinoma, facilitating the development of targeted treatments for this specific malignancy.
Accegen의 모든 제품들을 만나 보세요!
PRODUCTS
MSDS
온라인 견적