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Antibody System

[Antibodysystem] Depatuxizumab ELISA Kit

Cat-No. KDB86901

AntibodySystem는 Primary Antibody Biosimilar - Research Grade

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제품 설명

Depatuxizumab ELISA Kit

제품 번호

KDB86901

제품 특징

Catalog No.

KDB86901

Stability and Storage

The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.

Detection method

Colorimetric

Precision

CV<20%

Sample type

Plasma, Serum

Assay type

Quantitative

Sensitivity

0.156 μg/ml

Range

0.31-5 μg/mL

Recovery

80-120%

Specifications

Depatuxizumab

Alternative Names

ABT-806, ABT-414, unconjugate: ABT-806, CAS: 1471999-69-5

Background

Depatuxizumab Mafodotin (Depatux-M; ABT-414) is an antibody-drug conjugate consisting of a specific antibody against activated EGFR and a cytotoxic agent with antimicrotubule activity. The INTELLANCE 2/EORTC 1410 phase 2 trial produced interesting results for the combination regimen of Depatux-M and temozolomide in EGFR-amplified glioblastoma patients at first recurrence. For the first time worldwide, our work investigated the clinical outcome and safety of this combination in a real-life population.