(주)모아바이오

Antibody System

[Antibodysystem] Certolizumab ELISA Kit

Cat-No. KDB94402

AntibodySystem는 Primary Antibody Biosimilar - Research Grade

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제품 설명

Certolizumab ELISA Kit

제품 번호

KDB94402

제품 특징

Catalog No.

KDB94402

Stability and Storage

The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.

Detection method

Colorimetric

Precision

CV<20%

Sample type

Plasma, Serum

Assay type

Quantitative

Sensitivity

0.156 μg/ml

Range

0.31-5 μg/mL

Recovery

80-120%

Specifications

Certolizumab

Alternative Names

CDP870, PHA-738144, Certolizumab pegol, CAS: 428863-50-7

Background

Certolizumab pegol is a recombinant, humanized F(ab)’ fragment of an antibody conjugated to polyethylene glycol to enhance its plasma half-life. It does not contain an FC region and therefore does not cause antibody-dependent cell-mediated or complement-dependent cytotoxicity as described for infliximab, etanercept, and adalimumab. Another difference is that certolizumab pegol preferentially penetrates inflamed tissue compared to noninflamed tissue, and does so to a greater extent than adalimumab or infliximab. It is directed against soluble and membrane-associated human TNF-α and was approved for the treatment of Crohn’s disease that does not respond to conventional therapy in 2008 and for RA in 2009.