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YEASEN

[YEASEN] Neomycin Sulfate

Cat-No. 60207ES

YEASEN은 생명과학 연구 및 진단을 위한 고품질의 연구용 시약과 기기를 제공하는 글로벌 바이오 기업입니다.




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Neomycin Sulfate




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60207ES25 - 25g 

60207ES60 - 100g 




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Description

Neomycin sulfate from Yeasen is supplied in the form of white powder and is a USP-grade reagent with a solubility of about 200 mg/mL in water. It is an aminoglycoside antibiotic and can inhibit DNA degradation induced by DNase I.

Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S and 50S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate inhibits PLC (Phospholipase C) via binding to inositol phospholipids. It also inhibits phosphatidylcholine-PLD activity and induces Ca2+ mobilization and PLA2 activation in human platelets. Neomycin sulfate inhibits DNA degradation induced by DNase I.

Features

  • High-quality raw materials, all antibiotic product raw materials are sourced from high-quality fixed suppliers
  • Standardized production, using factory mass production mode
  • Wide range of applications, which can be used in the fields of molecular biology and biochemical experimental research of tissue culture
  • The cooperation platform covers the whole
  • To ensure product quality stability, the difference between batches is controlled within 1%

Applications

  • It is used to screen prokaryotes with resistance gene (neo)
  • Used for sterilization in cell culture
  • Inhibit DNA degradation induced by DNase I


Specifications

SynonymsNeomycin Sulfate
CAS#1405-10-3
FormulaC23H46N6O13·3H2SO4
Molecular Weight908.88
AppearanceWhite powder
GradeUSP
Potency (Anhydrous)≥ 600 μg/mg
SolubilitySoluble in water: ≥ 200 mg/mL
Structure


Components

Components No.Name60207ES2560207ES60
60207Neomycin Sulfate25 g100 g


Shipping and Storage

The product is transported and stored at room temperature, with a period of validity of three years.


Citations & References:

[1] Wu R, Mei X, Ye Y, et al. Zn(II)-curcumin solid dispersion impairs hepatocellular carcinoma growth and enhances chemotherapy by modulating gut microbiota-mediated zinc homeostasis. Pharmacol Res. 2019;150:104454. doi:10.1016/j.phrs.2019.104454(IF:7.658)

[2] Qiu Y, Yu J, Li Y, et al. Depletion of gut microbiota induces skeletal muscle atrophy by FXR-FGF15/19 signalling. Ann Med. 2021;53(1):508-522. doi:10.1080/07853890.2021.1900593(IF:4.709)




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