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제품 설명

PE Anti-Human CD4 Antibody[RPA-T4]

제품 번호

E-AB-F1109D

제품 특징

Product Details

Background	CD4, also known as T4/Leu-3, is a 55 kD single-chain type I transmembrane glycoprotein and member of the immunoglobulin superfamily. It is expressed on most thymocytes, helper T cells, type II NKT cells, and monocytes/macrophages. CD4 is part of the TCR/CD3 complex, binds to β2 domain from the MHC class II molecule, and participates in TCR signal transduction. CD4 is the receptor of IL-16 and is a coreceptor for the human immunodeficiency virus (HIV) and human herpes virus 7 (HHV-7).
Alternate Names	CD4,  T-cell surface antigen T4/Leu-3,  T-cell surface glycoprotein CD4
Swissprot	P01730
Clone No	RPA-T4
Host	Mouse
Reactivity	Human
Isotype	Mouse IgG1, κ
Isotype Control	PE Mouse IgG1, κ Isotype Control[MOPC-21]
Application	FCM
Form	Liquid
Conjugation	PE
Conjugation information	PE is designed to be excited by the Blue (488 nm), Green (532 nm) and Yellow-Green (561 nm) lasers and detected using an optical filter centered near 575 nm (e.g., a 585/42 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date	12 months
Shipping	Ice bag

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FAQ

• Q1:How to choose the CD4 of different clone numbers?

  CD4 [SK3] and CD4 [RM4-5] are used for cytokine testing. On the one hand, because PMA stimulation causes CD4 endocytosis, CD4 clones SK3 and RM4-5 have less effect on endocytosis. On the other hand, the experimental samples for the detection of cytokines need to be fixed, and the CD4 binding domains of SK3 and RM4-5 are less affected by fixators.

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