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제품 설명
Anti-SN-38 Mouse mAb
제품 번호
31905ES60 - 100 μg
31905ES80 - 1mg
제품 설명
SN38 is the active metabolite of the chemotherapy drug irinotecan (Camptosar). It is a topoisomerase I inhibitor, prevents the enzyme from properly resealing the DNA strands after they have been unwound, which leads to the accumulation of DNA damage.
Cat.No. | 31905ES60/31905ES80 |
Size | 100 μg/1 mg |
Source | Monoclonal anti-SN38 antibody, is produced from a hybridoma which was obtained from a mouse immunized with SN38. |
Buffer | 1×PBS, pH7.4. |
Type | Monoclonal Antibody |
Isotype | IgG1 |
Host | Mouse |
Concentration | 1 mg/mL |
Purity | ＞95% as determined by reduced SDS-PAGE ＞99% as determined by non-reduced SDS-PAGE > 99% as determined by SEC-HPLC |
Activity | EC50=80.5 ng/mL by ELISA |
Application | ELISA |
This product should be stored at -25~-15℃ for one year, do not freeze.
SDS-PAGE
Anti-SN-38 mouse mAb on SDS-PAGE under reduced condition. The purity is 95.5%；
Anti-SN-38 mouse mAb on SDS-PAGE under non-reduced condition. The purity is 99.2%.
SEC-HPLC
The purity of Anti-SN-38 mouse mAb is 100% as determined by SEC-HPLC.
ELISA Data
Dose response curve shows that the EC50 of Anti-SN-38 mouse mAb is 80.5 ng/mL.
Ver.EN20240725
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