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제품 설명
NanoGel dT20
제품 번호
Product Name | Pack Size | Cat. No. |
NanoGel dT20 10mL | 10mL | 17030-050150-2010 |
NanoGel dT20 30mL | 30mL | 17030-050150-2030 |
NanoGel dT20 50mL | 50mL | 17030-050150-2050 |
NanoGel dT20 100mL | 100mL | 17030-050150-2100 |
NanoGel dT20 300mL | 300mL | 17030-050150-2300 |
NanoGel dT20 500mL | 500mL | 17030-050150-2500 |
NanoGel dT20 1L | 1L | 17030-050150-1001 |
NanoGel dT20 5L | 5L | 17030-050150-1005 |
NanoGel dT20 10L | 10L | 17030-050150-1010 |
NanoGel dT20 50L | 50L | 17030-050150-1050 |
NanoGel dT20 100L | 100L | 17030-050150-1100 |
제품 특징
NanoGel dT20 was designed to address the selectivity and capacity requirements for large-scale downstream purification of a range of mRNA constructs used in vaccine and gene therapy applications. It can selectively captures the mRNA via the polyadenylated (polyA) tail using simple purification steps of salt for binding and water for elution. NanoGel dT20 effectively separates mRNA from components of the transcription reaction process, such as enzymes and plasmid DNA. It allows for a robust platform and efficient purification process for a range of mRNA molecules and applications.
Monodisperse matrix of very wide pores provides high binding capacity
Simplified workflow, high efficiency
Excellent scalability
Product Name | NanoGel dT20 |
Chromatography Technique | mRNA affinity |
Matrix | PS/DVB |
Particle Size | 50 µm |
Ligand | dT-20mer |
Dynamic Binding Capacity | ~ 2 mg·mL-1 (mRNA) |
Maximum Pressure | 3 MPa |
Clean In Place | 0.1 M NaOH |
Recommended Flow Velocity | 50-300 cm/h |
pH Stability | 2-13 |
Chemical Stability | Stable in commonly used buffers, 2 M HAc, 1 M HCl, 100% ethanol, isopropyl alcohol, etc. Avoid long-term exposure to strong oxidant, benzyl alcohol or tetrahydrofuran. |
Operational Temperature | 2-65 ℃ |
Storage | 20% Ethanol, 2-8 ℃ |
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