Proteogenix는 Primary Antibody Biosimilar - Research Grade
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제품 설명
제품 번호
PX-P5977
제품 특징
| Product name | VEGFA / VEGF165, C-His, recombinant protein |
|---|---|
| Origin species | Homo sapiens (Human) |
| Expression system | Eukaryotic expression |
| Molecular weight | 23.28 kDa |
| Protein delivered with Tag? | C-terminal His Tag |
| Purity estimated | >90% as determined by SDS-PAGE |
| Buffer | PBS, pH7.5 |
| Delivery condition | Dry Ice |
| Storage condition | 4°C for short term (1 week), -20°C or -80°C for long term (avoid freezing/thawing cycles; addition of 20-40% glycerol improves cryoprotection) |
| Brand | ProteoGenix |
| Host species | Mammalian cells |
| Applications | ELISA,WB |
| Fragment Type | Ala27-Arg191 |
| Protein Accession | P15692 |
| Reference | PX-P5977 |
| Note | For research use only |
VEGF165 is a member of the VEGF (vascular endothelial growth factor) family of proteins, which are composed of four structural domains: an N-terminal signal peptide, a pro-region, a VEGF homology domain and a C-terminal core domain. The VEGF165 protein is a 165-amino acid glycoprotein, which is secreted and binds to the extracellular matrix.
VEGF165 is a transcription factor that acts as a growth factor for endothelial cells, stimulating their proliferation and migration. It also regulates the formation of new blood vessels, or angiogenesis. Additionally, VEGF165 has been found to modulate the expression of other genes involved in angiogenesis, such as matrix metalloproteinases.
VEGF165 has a wide range of applications, including cancer therapy. It has been used as an antibody-drug target, as well as a therapeutic agent for the treatment of various types of cancer. Additionally, VEGF165 has been used to treat cardiovascular diseases, such as coronary artery disease, and has been investigated as a potential therapeutic agent for diabetic retinopathy.
QC & Validation Data
Immobilized VEGFA / VEGF165, C-His, recombinant protein (cat. No.PX-P5977) at 0.5µg/mL (100µL/well) can bind to Bevacizumab Biosimilar - Anti-VEGF mAb (cat. No.PX-TA1006) in indirect ELISA with Goat Anti-Human IgG secondary antibody coupled with HRP measured by OD450
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