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제품 설명

APC Anti-Human CD45 Antibody[HI30]

제품 번호

E-AB-F1137E

제품 특징

Product Details

Background	CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.
Alternate Names	CD45,  L-CA,  Ly-5,  Ptprc,  Receptor-type tyrosine-protein phosphatase C,  T200
Swissprot	P08575
Clone No	HI30
Host	Mouse
Reactivity	Human
Isotype	Mouse IgG1, κ
Isotype Control	APC Mouse IgG1, κ Isotype Control[MOPC-21]
Application	FCM
Form	Liquid
Conjugation	APC
Conjugation information	APC is designed to be excited by the Red (627-640 nm) laser and detected using an optical filter centered near 660 nm (e.g., a 660/20 nm bandpass filter).
Spectrum
Storage Buffer	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Storage	This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Expiration date	12 months
Shipping	Ice bag

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