MD Bioproducts는 생명공학 전문 회사로, 면역학 및 염증 연구를 위한 제품과 서비스를 제공합니다.

제품 설명

ST2L Human, Monoclonal Antibody, Biotinylated, 200 uL

제품 번호

101002B

제품 특징

Description

Human ST2L biotinylated  monoclonal antibody (Clone: B4E6, Host / Isotype Subclass: Mouse IgG1), for the identification and purification of human type 2 lymphocyte (Th2) subsets.
 
T1/ST2 (also known as IL-1 R4 or IL-33Ra) is a transmembrane glycoprotein expressed on mast cells and Th2 cells. It is a selective marker for human Th2 lymphocytes and plays a role in regulating inflammatory responses. IL-33 is a recently identified member of the IL-1 family of cytokines and is involved in Th2 mediated immune responses. IL-33 mediates its biological effects via T1/ST2 binding. The roles of IL-33 and T1/ST2 (IL-33Ra) have been investigated in many immune responses such as allergy, asthma, rheumatoid arthritis and osteoarthritis.

Data/Specifications: 

• Clone: B4E6
• Host / Isotype Subclass: Mouse IgG1
• Form: The biotinylated antibody is supplied in PBS and purified over protein G-sepharose from concentrated tissue culture supernatant. The antibody is supplied with 0.1% sodium azide as preservative.
• Specificity: This clone recognizes hST2L specifically on the cell surface of human type 2 (Th2, Tc2, NK2 and NKT2) but not type 1 lymphocytes