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제품 설명 

Research Grade Ulocuplumab

제품 번호

DHF39901

제품 특징

Description

Ulocuplumab (BMS-936564) is a first-in-class fully human IgG4 monoclonal anti-CXCR4 antibody that inhibits the binding of CXCR4 to CXCL12. The CXCR4/CXCL12 (SDF-1) axis has been known for many years as a critical regulator of tumor proliferation, cell, as well as migration into and out of the bone marrow.

Catalog No.

DHF39901

Host species

Homo sapiens

Species reactivity

Human

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Concentration

1.59 mg/ml

Purity

>95% by SDS-PAGE.

Clonality

Monoclonal

Isotype

IgG4-kappa

Applications

Research Grade Biosimilar

Target

Stromal cell-derived factor 1 receptor, LCR1, HM89, LPS-associated protein 3, LAP-3, CXC-R4, CXCR-4, SDF-1 receptor, CD184, NPYRL, LESTR, Fusin, FB22, C-X-C chemokine receptor type 4, CXCR4, Lipopolysaccharide-associated protein 3, Leukocyte-derived seven transmembrane domain receptor

Purification

Protein A or G purified from cell culture supernatant.

Endotoxin level

Please contact with the lab for this information.

Expression system

XtenCHO

Accession

P61073

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.

Alternative Names

BMS-936564, MDX-1338, MDX1338，CAS: 1375830-34-4

Note

For research use only. Not suitable for clinical or therapeutic use.

Data Image

• 

  SDS-PAGE
  SDS PAGE for Ulocuplumab
• 

  SEC-HPLC
  The purity of this product is >95% as determined by SEC-MALS.

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