The SERION ELISA classic Influenza A and Influenza B Virus IgA, IgG and IgM tests are quantitative and qualitative immunoassays for the detection of human antibodies in serum or plasma directed against conserved nucleo- and matrix proteins of Influenza A or B Viruses. The SERION ELISA classic Influenza A and B Virus IgM tests are recommended for the sensitive detection of acute infections, particularly in children. The specific SERION ELISA classic Influenza A and B Virus IgA and IgG tests allow for the differentiation between acute and previous infections. The SERION ELISA classic Influenza A and B Virus IgG tests have been validated for the demonstration of intrathecally synthesized antibodies in CSF diagnostics.
Highlights
Use of conserved nucleo- (NP) and matrix proteins (M) for the detection of antibodies directed against Influenza A and B Viruses, independent of the causative virus subtype
Sensitive demonstration of IgM antibodies for detection of acute / primary infections
Exclusion of background seroprevalence of IgA and IgG antibodies resulting in the specific detection of clinically relevant antibody activities
Alternative IgA and IgG borderline ranges for children and adults
Differentiation of acute from past infections
Typification of Influenza A and B Virus infections by combined usage of SERION ELISA classic Influenza A and B Virus tests
Detection of intrathecally synthesized Influenza A or B Virus IgG antibodies for CSF diagnostics
MSDS
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